| First Published on Clinicaltrials.gov: |
2/8/2009 |
| Status: |
Ongoing, But Not Recruiting |
| ClinicalTrials.gov ID: |
NCT00958048 |
| Sponsor: |
National Taiwan University Hospital |
| Purpose: |
Specific aims:
Aim 1. To determine the incidence of hypoventilation in Amyotrophic Lateral Sclerosis (ALS) patients.
Aim 2. To identify the clinical characteristics and risk factors associated .
Aim 3. To determine the effect of early intervention with nocturnal NIV on the prognosis of ALS patients.
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| Phase: |
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| Treatment Type: |
Device |
| Trial Type: |
Open Label |
| Estimated Enrollment: |
70 |
| Eligibility: |
18 years and older. Both genders. No healthy volunteers. |
| Details: |
Hypoventilation at ALS patients who had relatively preserved respiratory muscle function and no respiratory failure at clinical sleep was common, early identification through PSG screening and PtcCO2 will allow for the early diagnosis and intervention. Understanding the time of applying NIV and the effect on prognosis in ALS will allow for the early intervention and prediction of outcomes. |
| Collaborator(s): |
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| Location(s): |
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| Primary Investigator: |
Peilin Lee, M.D. & Whey Dong Wu, M.D., National Taiwan University Hospital |
| Contact: |
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| Trial Protocol as Published on Clinicaltrials.gov: |
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| ALS Forum: |
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