ALS Closed Clinical trials information

Closed Clinical Trials

For many ALS patients, participating in clinical trials gives them the sense of having some control over the course of their disease and an active hand in their treatment. There are other benefits as well. You'll have access to therapeutics before they've reached the marketplace and high-level medical care at top research hospitals. But perhaps most importantly, you'll know that your participation is a priceless contribution to the search for an ALS cure

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Closed Trials (61)

Description for Closed Trials

Recent Updates

TDI-144 - 2/10/12 - We moved this small molecule targeting cellular stress into the a...
TDI-143 - 5/7/12 - This biologic targeting endothelial cell dysfunction moved into ef...

Trial Stage Recruiting Sponsor
Feasibility of Telesurveillance and Home Cough Assistance for ALS IV This study has been completed Fondazione Salvatore Maugeri
Safety and Tolerability of the Ketogenic Diet in Amyotrophic Lateral Sclerosis (ALS) III This study has been terminated Johns Hopkins University
An Open-label, 8-week, Flexible Dose Trial of Escitalopram (Lexapro®) in Comorbid Major Depression and Amyotrophic Lateral Sclerosis III This study has been completed University of South Carolina
Insulin-like Growth Factor-1 (IGF-1) in ALS III This study has been completed Mayo Clinic
Expanded Controlled Study of Safety and Efficacy of MCI-186 in Patients With ALS III This study has been completed Mitsubishi Tanabe Pharma Corporation
Efficacy and Safety Study of MCI-186 for Treatment of ALS III This study has been completed Mitsubishi Tanabe Pharma Corporation
Efficacy and Safety Study of MCI-186 for Treatment of ALS Who Met Severity Classification III III This study has been completed Mitsubishi Tanabe Pharma Corporation
Study to Investigate the Safety and Efficacy of Lithium in Volunteers With ALS II/III This study has been terminated Massachusetts General Hospital
Safety and Efficacy of TRO19622 as add-on Therapy to Riluzole Versus Placebo in Treatment of Patients Suffering From ALS (MITOTARGET) II/III This study has been completed Trophos
Repetitive Transcranial Magnetic Stimulation (rTMS) in ALS II/III This study has been completed Catholic University of the Sacred Heart
Safety Extension Study of TRO19622 in ALS II/III This study has been completed Trophos
Study of Myobloc in the Treatment of Sialorrhea (Drooling) in Patients With ALS II/III This study has been completed The University of Texas Health Science Center at San Antonio
Memantine for Disability in Amyotrophic Lateral Sclerosis (MEDALS) II/III This study has been completed University of Lisbon
Talampanel Clinical Trial in ALS Patients II This study has been terminated Teva Pharmaceutical Industries
Pilot-Study of Thalidomide in ALS II This study has been terminated Charite University
Study of Pioglitazone in Patients With ALS II This study has been terminated University of Ulm
Tretinoin and Pioglitazone HCL in patients with ALS who are Currently on Riluzole II This study has been completed Phoenix Neurological Associates, LTD
Single-Ascending-Dose Safety/Tolerability of NP001 (Neuraltus) II This study has been completed Neuraltus Pharmaceuticals, Inc.
A Study of CK-2017357 in Patients With Amyotrophic Lateral Sclerosis(ALS) II This study has been completed Cytokinetics
The Effect of Memantine on Functional Outcomes and Motor Neuron Degeneration in ALS II This study has been completed University of Alberta
Clinical Trial of SB-509 in Subjects With Amyotrophic Lateral Sclerosis (ALS) II This study has been completed Sangamo Biosciences
Tamoxifen Therapy in ALS II This study has been completed University of Wisconsin, Madison
Phase II Study Using Thalidomide for the Treatment of ALS II This study has been completed Dartmouth-Hitchcock Medical Center
Combination Therapy Selection Trial in ALS II This study has been completed Columbia University
Growth Hormone in ALS II This study has been completed Federico II University
Clinical Trial of High Dose CoQ10 in ALS II This study has been completed Columbia University
Safety and Tolerability Study of KNS-760704 in ALS II This study has been completed Knopp Neurosciences
A Phase II Multi-Centre, Extension Study to Investigate the Long Term Safety of ONO-2506PO in Patients Diagnosed With ALS II This study has been completed Ono Pharma
Placebo Controlled Study of ONO2506PO in the Presence of Riluzole in Patients With ALS II This study has been completed Ono Pharma
A Study to Evaluate the Effects of Multiple Doses of CK-2017357 in Patients With ALS II This study has been completed Cytokinetics
A Multicenter, Dose Ranging Safety and Pharmacokinetics Study of Arimoclomol in ALS II This study has been completed CytRx
A Long-Term Extension Study of TCH346 and Placebo Administered Once Daily in Patients With Amyotrophic Lateral Sclerosis(ALS) II This study has been completed Novartis
Study Evaluating TCH346 and Placebo Administered Once Daily in Patients With ALS II This study has been completed Novartis
G-CSF Treatment for ALS: A RCT Study Assessing Clinical Response II This study has been completed Peking University
Clinical Trial of Glatiramer Acetate in ALS II This study has been completed Teva Pharmaceutical Industries
Tamoxifen Therapy in ALS II This study has been completed University of Wisconsin, Madison
Dose Titration Study to Test Safety and Effects of CK-2017357 in Patients II This study has been completed Cytokinetics
The Effect of Intensive Controlled Exercise in the Early Stages of ALS I/II This study has been terminated Radboud University
A Safety and Tolerability Study of Intracerebroventricular Administration of sNN0029 I/II This study has been completed NeuroNova AB
Safety Study of Oral Sodium Phenylbutyrate in Subjects With ALS I/II This study has been completed Department of Veterans Affairs
Safety Study of High Doses of Zinc in ALS Patients I/II This study has been completed Phoenix Neurological Associates, LTD
R(+)PPX High Dose Treatment of ALS I/II This study has been completed Bennett, James P., Jr., M.D., Ph.D.
Combination Therapy in ALS (PNA) I/II This study has been completed Phoenix Neurological Associates, LTD
R(+) Pramipexole in Early ALS I/II This study has been completed Bennett, James P., Jr., M.D., Ph.D.
Clinical Trial on the Use of Autologous Bone Marrow Stem Cells in (CMN/ELA) I/II This study has been completed Fundacion para la Formacion e Investigacion Sanitarias de la Region de Murcia
Safety and Tolerability of the Ketogenic Diet in ALS I This study has been terminated Weill Medical College of Cornell University
Safety, Tolerability, and Activity Study of ISIS SOD1Rx to Treat Familial Amyotrophic Lateral Sclerosis (ALS) Caused by SOD1 Gene Mutations (SOD-1) I This study has been completed Isis Pharmaceuticals
First Time in Human Study of GSK1223249 in Amyotrophic Lateral Sclerosis I This study has been completed GlaxoSmithKline
Mesenchymal Stem Cells for Treatment of ALS (Mayo Clinic) I This study has been completed Mayo Clinic
Amyotrophic Lateral Sclerosis and Frontotemporal Dementia I This study has been completed Assistance Publique - Hôpitaux de Paris
Efficacy of Noninvasive Ventilation This study has been completed Columbia University
A P300 Brain Computer Interface Keyboard to Control Assistive Technology For Use by People With ALS This study has been completed University of Michigan
Lithium Carbonate for patients with ALS This study has been completed King's College London (UK)
National Registry of Veterans With Amyotrophic Lateral Sclerosis and DNA Bank (ALS Registry) This study has been completed Department of Veterans Affairs
Open Label Study of efficacy with Co-Q10- enzyme in ALS This study has been completed Eleanor and Lou Gehrig ALS Center at Columbia University
Muscle Ultrasound: A New Tool for Measuring Progression in ALS This study has been completed Vanderbilt University
Amyotrophic Lateral Sclerosis (ALS) Gulf War Study This study has been completed Department of Veterans Affairs
Exposure to Neurotoxins as Risk Factors for ALS This study has been completed National Institute of Environmental Health Sciences (NIEHS)
Confirmation of Self-Reported Incident ALS Cases in the AARP-Diet and Health (AARP-DH) Cohort This study has been completed National Institute of Environmental Health Sciences (NIEHS)
ALS Web Based Patient Care Database: ALSConnection.Org This study has been completed Forbes Norris MDA/ALS Research Center
Randomized Placebo-Controlled Crossover Trial With THC (Delta 9-Tetrahydrocannabinol) for the Treatment of Cramps in ALS This study has been completed Cantonal Hospital of St. Gallen